Causes, Inheritance: Many steps to cancer

In Familial Adenomatous Polyposis, a complex cascade of events leads from an initial mutation in a “gatekeeper” gene, eventually to a malignant tumor.

Educational standards - statements

• Gene mutation in a cell can result in uncontrolled division called cancer. Exposure of cells to certain chemicals and radiation increases mutations and thus the chance of cancer.| AAAS#5C/H6
• Much can be learned about the internal workings of science and the nature of science from study of individual scientists, their daily work, and their efforts to advance scientific knowledge in their area of study.| NSES#G 3.1

Dolan DNA Learning Center © 2008, Cold Spring Harbor Laboratory. All rights reserved.

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