Hallmarks, Promoting mutations

Bruce Stillman, Ph.D., president of Cold Spring Harbor Laboratory, explains that genomic instability is a characteristic of cancer cells.

Educational standards - statements

  • Gene mutation in a cell can result in uncontrolled division called cancer. Exposure of cells to certain chemicals and radiation increases mutations and thus the chance of cancer.| AAAS#5C/H6
  • Genes are segments of DNA molecules. Inserting, deleting, or substituting segments of DNA molecules can alter genes. An altered gene may be passed on to every cell that develops from it. The resulting features may help, harm, or have little or no effect on the offspring's success in its environment.| AAAS#5B/H4
  • Changes in DNA (mutations) occur spontaneously at low rates. Some of these changes make no difference to the organism, whereas others can change cells and organisms. Only mutations in germ cells can create the variation that changes an organism's offsprin| NSES#C 2.3
  • Given adequate resources and an absence of disease or predators, populations of organisms in ecosystems increase at rapid rates. Finite resources and other factors limit their growth| AAAS#5D/M3
  • Populations can reach limits to growth. Carrying capacity is the maximum number of individuals that can be supported in a given environment. The limitation is not the availability of space, but the number of people in relation to resources and capacity of earth systems to support human beings.| NSES#F 2.3
  • Much can be learned about the internal workings of science and the nature of science from study of individual scientists, their daily work, and their efforts to advance scientific knowledge in their area of study.| NSES#G 3.1